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Turkish Archives of Otolaryngology 2006; 44(4): 223-226 Abstract |
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Full Text in English [PDF] 207 KB |
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Effect
of ketamine anaesthesia on middle ear pressure in rabbits: a pilot study
Tavşanlarda orta kulak basıncı üzerine ketamin anestezisinin etkisi: pilot çalışma B. Kocaman*, Ö. Öztürk**, Y. Demiraran*, C. Aldırmaz Ağartan***, E. Egeli** |
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| *Department of Anaesthesiology, **Department of Otolaryngology, Head & Neck Surgery, and ***Department of Pediatric Surgery, Düzce Medical Faculty, Abant İzzet Baysal University, Bolu, Turkey |
| Key Words |
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| Ketamine, tympanometry, middle ear pressure, saline, rabbit |
| Abstract |
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Objectives:
Although most studies about effect of anaesthetics on middle ear
pressure were explained with gas effect there are no studies about
effect of ketamine on middle ear pressure. The aim of this study was to
evaluate the effect of ketamine anaesthesia on middle ear pressure. Methods:
Male New Zealand rabbits (n=15), weighing between 2.5-3.2 kg were
randomly divided into two groups. Those in Group I (n=9) were
anaesthetized by intravenous ketamine 50 mg.kg-1 whilst Group II (n=6)
were injected with the same volume of saline. Baseline tympanometry
readings were performed on the left and right ears after otoscopy
examination and again at 5 and 20 minutes. Results:
The change of tympanometric measurements before ketamine, at 5th and
20th minutes of the administration was no statistically significant in
both of Group I and II (p>0.05). There was a slightly significant
difference at 20th min of administration when ketamine group compared
with control group (-55.6±29.5 in Group I; -29.0±33.5 in Group II)
(p=0.03). Conclusion: In this study it is concluded that ketamine anaesthesia has no effect on the pressure in middle ear. |
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| Accepted after revision: | July 17, 2006 | ||
| Correspondence: |
Özcan Öztürk, MD PK 8 81010 Düzce -Türkiye Fax: (0380) 541 41 05, (0380) 541 42 13 e-mail: ozturko_70@yahoo.com |
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Copyright © 2006-2007 by the Turkish Otolaryngology & Head and Neck Surgery Foundation. |
